Before Using This medicine: This product should be used with caution due to the possible interaction of Retin-A with related external medication, abrasive soaps, drying cosmetics and products with high alcohol content. Care should also be taken regarding the application of preparations containing sulphur, resorcinol or salicylic acid.

Other Medical Problems: If you have been previously treated with keratolytic preparations or exfoliants, you should wait until any skin rash clears up before beginning even low strength treatment. Studies of the effect of this product on pregnant women are incomplete. For this reason, it should only be applied when absolutely necessary and always under a doctor's supervision. The effectiveness of Retin-A is almost always accompanied by skin irritation. In the treatment of acne, this phenomenon is directly related to the effectiveness of the product and disappears once applications are more spaced out. Cosmetics may be used, but clean skin thoroughly before applying the medication.

Proper Use of This Medicine: Apply once a day at bedtime.

Precautions While Using This Medicine: Retin-A is very safe when used as directed. Several studies show Retin-A is safe to use during pregnancy, however you should only use Retin-A during pregnancy if this is OK with your obstetrician. Do not smoke while applying Retin-A, the gel form is flammable.

Side Effects of This Medicine: Due to the possibility of irritation, it is advisable to begin treatment on a small area of skin. Exposure to the sun or to ultraviolet rays causes additional irritation. During treatment, such exposure should be avoided as much as possible or a sun block should be used. During the first weeks of treatment there may be an apparent worsening of the problem. Such a reaction is perfectly normal because small cysts deep within the skin are being eliminated at an accelerated rate. This medication can increase sensitivity wind and cold. Avoid prolonged exposure to the sun and sunlamps. Wear protective clothing and use an effective sunscreen. If any ingredient should cause hypersensitivity, discontinue use.